Just got EU3, and this my first real game (my first two were abandoned). Playing as Castille --> Spain, and the year is 1548. I've got historical lucky nations on because, well, I wanted it to be roughly historical.
But of course, lucky nations is never a guarantee. Lithuania and Poland ate up the Golden Horde like mad, thus leaving the "lucky" Muscowy an OPM for almost the entire game, which is kind of funny.
Although, it's also a shame that from the looks of things, Russia will never form. In my previous two games, Muscowy stretched from the Baltic Sea almost all the way to Ming.
Incidentally, I'm using the Age of Discovery mod as well, which, for those of you who don't know, adds a lot of native nations to the New World (mostly hordes, some normal). It makes colonization so much more realistic, even if it does get tedious and frustrating sometimes, dealing with all those nationalist/patriot native rebels.
My goals are to colonize somewhat historically. I plan to own all of South America and modern Mexico by the end of the game. As you can see here, I own most of Brazil and the Yucatan peninsula:
Portugal is my vassal, and I'm pretty much just leaving them to their own devices, so long as they don't get in my way. I'm letting them colonize the West Indies, which I don't care about at all.
They're also a somewhat useful ally, considering the rest of Europe hates me, and I have no idea why. I have close to 0 infamy, but no other country will ally with me or even enter a royal marriage with me. The only countries I've ever antagonized are Portugal (to force vassalize them), Aragon (for obvious reasons) and France.
It's a funny story with France, actually. I guaranteed Navarra on day 1 to stop the French from meddling, but then when I was preoccupied in another war, the bastards ate Navarra and I didn't get called to war. I didn't even notice until it was too late. The only good that came of it was I later got one of those border dispute events which gave me a core on Navarra. Then for the longest time I was unable to take on Aragon because France warned me. Then one I day I checked the ledger to see who had the biggest armies, and France was at zero. That's right. Zero. No idea how it happened, but as soon as I saw that, I declared a reconquest war on them for Navarra, chucked 30,000 troops over the border, and managed to occupy 4 or 5 of their provinces before I saw French doomstacks emerging from the fog of war. So I was able to peace out for not only Navarra, but also a handsome 400 ducats.
The only real downside of the AoD mod is that the AI just isn't meant for it. Most of the time, the AI is too stupid to send troops to the New World
before it colonizes, which means their colonies usually end up getting seized by the hordes almost immediately. Of course, I haven't seen that happen in this game yet. The only other real colonizer besides me and Portugal looks to be GB, who owns a lot of the West Indies, but I have yet to see them (or Portugal) establish a mainland colony at all.