From what I've seen most of the time it's just a waste of relations with the target, your royal marriage partners and of your prestige. You get a casus belli when the target is of the same dynasty, but how does it work otherwise?
If there is an heir with a weak claim, does your claim hold on until their dynasty recovers legitimacy or until there is a new king/queen with a good claim?
If a monarch dies with no heir and you are claiming do you instantly get a PU?
If there is an heir with a weak claim, does your claim hold on until their dynasty recovers legitimacy or until there is a new king/queen with a good claim?
If a monarch dies with no heir and you are claiming do you instantly get a PU?