If you have WoL you can choose carousing which has. 30% chance to remove stressed/depressed, choose seduction to get a lover or ten to get the "comforted by lover" status which should always remove stressed/depressed, hunting and hope the hunting dog fires the event, or you can hope that a content courier successfully fires the event.
For the best % chance then of losing this, would you say carousing is the way to go?