Candar vs Ottomans is easy. No matter who they DoW it won't be you and you can finish your siege before they do. Slightly RNG dependent.
Meanwhile you can siege down everything east of Ankara for free WS, WE and 'occupied and besieged provinces'.
Not to mention that you can pick up quite a few allies if Ottos sit it out, then DoW with promise of land and break your promise.
And as with any nation that's going to war against the Ottomans: If you win the first war you've won the game. You're going to end up playing an Ottoman Empire imposter with slightly less ideal NIs. Easy mode.
Really confusing why you don't see more people picking up Turkish Delight, but I guess they're being deterred and don't even bother trying.
DoW with Mamluks
Complete collapse in 1489
Ottos are only difficult if they get their cores back. Without them they're a breeze in the wind as long as you're sitting in their eastern half. West has a bit more trouble.