I really hope the upcoming Wealth of Nations DLC has some form of dynamic trade routes. It would be fabulous to be able to either reverse the direction of trade between two nodes (in order to, say, make trade flow from Antwerpen to London or from Panama to Mexico) to to create entirely new connections between nodes (so, if for example Japan colonizes the Philipines, then it could route trade from there to Nippon.) Of course, you'd have to work to ensure that no closed loops form, but that should be relatively easy to arrange. Either prevent any action that would close a loop or make it such that when a loop is closed, some other connection in the loop dissipates (perhaps the connection carrying the smallest amount of trade?)
Dynamic trade routes would allow for the sandbox altering history approach that permeates the rest of the game to come to trade as well.
Dynamic trade routes would allow for the sandbox altering history approach that permeates the rest of the game to come to trade as well.