Forget about Spain, what's going on with the Black Sea? Tuscany and Ukraine?
Ah yes, I believe Tuscany ate Genoa and carved out some land for themselves based on the Genoan holdings. Ukraine has been pretty aggressive, it managed to basically destroy my ally Crimea (I couldn't defend it well enough against an alliance of Ukraine, Muscovy and some other neighbours, my Ottomans were mainly focused on the Balkans.