My game hasnt arrived yet so I dont know if they're in it or not, but Im guessing they arent. For much of their history they had primarily Genovese holdings, and I know that isnt playable without a patch, however once they siezed Monte Carlo during the Gu-Gh conflict they really ruled as princes. It would make sense to make them a playable family ruling over Nice, which they controlled almost entirely, for a long period of time when it was broken away from Genova because of the Ghibelline take over.