I am another who does not use CK2+, because frankly, it should be called CK2+++++, or whatever - you cannot seriously expect to appreciate all the changes it makes everywhere, can you? It "fixes" everything. Mind you, I do appreciate Wiz working on the AI for the Dev Team, because that - I do recognize as one hell of an useful thing to happen.
I personally do not touch most mods unless it is for fantasy scenarios like aGoT. I maintain my own personal mod that I tweak whenever I want to get balance or something done right - a pain to keep up every new patch, sure, but far better than being stressful about other mods updating themselves and nitpicking between features I do, and do not like.