It sure is.
You'll need to unlock the district feature (It's pretty early if I recall correctly), then look at your resources map and spot some green ground - This is meadow, which provides the soil that farmland needs (You -can- place farmland elsewhere, but nothing will grow naturally - the farms will import soil through trucks)
Once you've found a good location, drag out some dirt roads and make it all nice (Not mandatory but hey - it's a city builder. Might as well pretty it up), then paint a district over the entire area, pick the farming district tool and click on the district you've made (It should have a tractor icon)
Done? Zone it with industrial, connect it up with pipes and power and wait. You may also want to build a fire station nearby as well as give them the smoke detector policy - industry has a tendency to burn a lot.