If you want to very easily get Turn the Tables:
Start as Portugal
Break Alliance with England and make friends with Castile. Sell off Fez if either Berber doesn't rival you, or else just let it revolt away.
Split off 3 light ships and give them each an explorer
Send them off west, you MUST discover Bermuda and you want to reveal every piece of coast from the Gulf of Mexico up to Abnaki, iirc. Anything else (Caribbean, Africa, South America) is totally irrelevant.
Pick Exploration idea set.
With the range boost from Exploration, you can colonize Bermuda, which has no natives and therefore you don't need to send ships or troops.
From Bermuda you can colonize the East Coast and get a colonial nation going in 13 colonies region.
Take Expansion to speed things up.
Colonize everything that would add to your colonial nation and kill off nations within the region too.
Now here's the kicker : colonize a SINGLE province outside the 13 Colonies colonial region to the southwest (around like, Louisiana, I forget the province name and don't have the game open))
Sell all your islands and Iberian provinces except your capital to your colonial nation (or Castile, if you plan to never visit Europe again)
Move capital from Lisboa to the single non-colonial nation province you have in N.A.
Sell Lisboa.
Crank up Tariffs until liberty is at 55%+, release colonial nation and play as them, send diplomat to Portugal to ally, marry, and boost relations, then happily diplo-vassalize your OPM former lord.
Form USA and : quit from boredom / use former Portugal as a landing ground for European invasion