Lets just say I'm newbish enough to feel this is warranted when playing the Byzantines, I don't feel like another bankruptcy. 
o
o-
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Just give yourself 300 ducats and wait for the loan repayment screen to come up. In all seriousness I'd tell us, but I don't have the game with me right now to point out exactly how.
In a save game you'll see lines like this just above your cities.
just delete it and the loan is gone. (Make sure you do it your country and not another.)
Code:
loan = {
id = { type = 4712 id = 24508013 }
tag = bank
interest = 5
amount = 200
expirydate = { year = 1746 month = december day = 0 }
}just delete it and the loan is gone. (Make sure you do it your country and not another.
)