As for money, first step is to set the tax sliders to at least 50% for the first few months, and increase tariffs if that's still not enough money to break even. Then you want to set your National Focus point (or points, if you have more than one) to increase the hiring of Administrators/Bureaucrats, starting in your highest income regions. That will boost Administrative Efficiency and give you more tax money for the same tax rate. You also want to put your Administrative salaries at over 50%, if possible, to promote the hiring of bureaucrats. Once a region gets to at least 80%, I move the NF point elsewhere, and may even back down my administrative salaries, because increasing numbers of bureaucrats and tax-related techs will push that over 100% eventually, and anything over 100% is wasted, while you still need to pay those excess bureaucrats.
Once you've got a stable positive income and enough money to get past any short-term dips, you can start reducing your tax and tariff sliders a little, and increase the pay of your Educators/Clerics to improve Literacy. Then you build a factory, once you have the spare cash for the facility, the initial input materials, and operating capital to see it through the first few months until it (hopefully) breaks even and starts turning a profit.