Christianity existing to unite Europe? Luck.
Columbus screwing up Italian and Arabic miles but still reaching the New World? Luck.
The Aztecs having the gold Europe needed when the Ottomans were about to cause a continental economic crash? Luck.
The natives who owned those resources being extremely vulnerable to Old World diseases? Luck.
The Aztec capital encountering a famine right as the Spanish-led coalition is on its doorstep? Luck.
All of this happening as the Inca, people who based their Empire's legitimacy on its ability to expand their borders and who built a massive road along the Empire, running out of land to conquer? Luck.
South America being covered in mineral riches? Luck.
The North Sea being just inhospitable enough for the British to be able to get away with privateering Spanish gold? Luck.
An ocean route to India existing? Luck.
The Muslims who occupied Iberia just happening to have the technology required to sail for long distances, but not using it for Atlantic exploration earlier?
Africans being able to survive the working conditions for farming sugar? Luck.
Kilwans lacking the ability to fight off Portuguese exploration vessels? Luck.
The Indian Ocean being chock full of goods that would sell well in Europe, right as the Europeans came into possession of extremely high amounts of mineral wealth through the Americas? Luck.
Literally everything that happened in India? Luck.
They were given a technological catch-up button with the Silk Road and the fall of the Byzantine Empire, a crap ton of mineral wealth from the Americas, sailing technology from the Muslims, and the perfect position for snowballing, since they got their wealth by looting the existing trade routes from half the globe away. All the while, Eastern Europeans were loyal enough to their faith, something they got from Israel, to defend them instead of turning on them to loot them for the gold they were bringing in.
If Europe was playing according to the same rules as everyone else, they would've collapsed from the Ottoman disruption of the Silk Road's trade. They would not have found two continents full of Deus Ex Machina set specifically to be easily conquered right as the Europeans arrived.