425k people it performs great! Down to 20 average FPS is nothing special, but on top of that you have got 1GB VRAM version of 650ti so here s possibility to have game slowed due to this.
Try lower texture quality to medium or low... of course even if it helped it's up to you... more FPS or nice graphics

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Shadowplay will work for 650ti too. Unfortunately I can not guarantee that your FPS remain untouched.
Sorry, I wasn't clear on my post. My post was to show how well my tiny i3 processor and lowly 650 Ti can run this game with unlocked 25-tile that is 3/4 of the way full.
I mean minimum requirements is a quad core CPU, and recommended requirements is GTX 660 and both requirements are for 9-tile cities. I'm at over 15-tiles on the default high settings and still very playable. Which requirements say I shouldn't even be able to play even on lowest settings.
"heaven" is have or haven't :-D? Where is GTX 780 with that superproccesor? If you tried to capture on the more powerful PC, please
http://www.technize.net/wp-content/uploads/2012/11/CPU-utilization-of-logical-processors.jpg . I am very interested in usage of all threads.
It is, "I have the same issue with my i7 and 780 with the graphics lag when zooming in. I mean my i3 has nearly the same performance as my main gaming rig. There is definitely some optimization issues with the game still.
as for CPU usage on my i7, it is about 60% on speed 1, and nearly 100% on speed 3. My i3 is 100% at any speed.
I have noticed though, that if I increase game speed to speed 2 or speed 3, the game stayed at speed 1. I thought maybe this was the capture mode or something. But on retest without capture or anything running but 25-tile and fps mod, the game still doesn't process the faster speeds. I believe it to be related to the 100% CPU usage. The game can't run any faster as the CPU has no more resources.
on my i7, I can get a big bump from speed 1 to speed 2, but when I go from speed 2 to speed 3, it is just a tiny gain, so unnoticeable I had to zoom into a freeway to notice the tiny increase in speed. It may also be related to very full cpu usage.
So if you can run the multi-speeds fine in early games and can't in mid or late game, then your CPU may be the issue.
I'll try to test my i7 later and upload the video results.