Did a little hands-off (to 1688) and here is what I saw:
Cuzco died out quickly as only Inca and Chimu knew about it and were stagnant at 5 each. Trade went to Ganges and Malacca. Zacatecas would have met the same fate had not the NA tribes sent their merchants there with about a year to spare. Muscat died off and was replaced by Tiracambu, which never saw another merchant and withered away. Zanzibar fell next, replaced by Rufiji, which then replaced itself. Ivoiria was replaced by Adwaghost, which replaced itself later. Barahona (England) was created at no expense to another CoT, had not died by CTD. I expect that these results are not likely to vary without human player interference
Cuzco died out quickly as only Inca and Chimu knew about it and were stagnant at 5 each. Trade went to Ganges and Malacca. Zacatecas would have met the same fate had not the NA tribes sent their merchants there with about a year to spare. Muscat died off and was replaced by Tiracambu, which never saw another merchant and withered away. Zanzibar fell next, replaced by Rufiji, which then replaced itself. Ivoiria was replaced by Adwaghost, which replaced itself later. Barahona (England) was created at no expense to another CoT, had not died by CTD. I expect that these results are not likely to vary without human player interference