Aside from women not being able to be ordained priests or bishops (though medieval abbesses were extremely powerful and influential in their realms) , and inheritance being passed along the male line, nah there really shouldn’t be any sort of opinion penalties from vassals against a female ruler, save for maybe dynastic loyalists.
Dynasties obviously preferred not to have a female heir because it would mean the kingdom would almost invariably pass on from their dynasty to another one, so dynastic vassals or ones that are very loyal to their lieges would probably have a problem, but everyone else, probably not.
Yeah, I very much agree with this.
It was pretty normal for wives to rule territory in their husbands' absence, even for long periods of time and in the face of sieges etc., and for mothers to act as regents. As that was expected of them, most people probably accepted on some level that women were capable of ruling, and if the woman in question had broad support of the court/nobility/church there wasn't much of an issue in just letting her rule.
If she didn't have that support, though, her womanhood presented an easy target to undermine her legitimacy. And of course you always get people who are more hard-line misogynist and people who are more egalitarian, aside from the more practical dynastic concerns.
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