Yes but they depend on each other indirectly which makes each dome needing its own requirement which need their own buildings. In early game when i have 2 domes, and i didn't have the fungi farm i had to build extra farms but i didn't have space in my two domes as it had other buildings, this may be okay in later stage but it still shows how each type of building in every dome is inefficient than all of them in one dome.If it's a situation where there is disagreement about what the core mechanics should be, why can't mods be the solution?! Squad is fundamentally opposed to delta-v readouts in Kerbal Space Program. A huge percentage of the community uses a mod to display delta-v and we are all happy. Firaxis thought it was very important for game balance and pacing to have turn limits in XCOM 2, but a huge portion of the community found them frustrating and unfun, so lots of players use a mod that increases or eliminates turn limits. Everyone is happy. At the end of the day it's a game and what matters is that players are having fun.
You still have a cohesive colony with self-contained domes, because those domes all depend on each other. Everyone depends on the dome with the University to produce skilled colonists for all the facilities in the various domes. Everyone depends on the dome with the machine parts factory to supply maintenance resources for critical systems. You can make a similar argument for the dome with the research facility, the surplus food production, and the rare metal extractor workers.