I'm not the guy starting in Greenland. I started in Mexico, just north of the natives. His topic did make me want to finally do this though.
I started there so I could both fight the natives, and also have a decent chance of getting gold in my first five provinces. I got a gold mine, so I'm pretty pleased with my start. Starting south of the Mexican natives is probably optimal, but I was playing the short game on trade. I wanted to dominate the Mexico node, the Caribbean, followed by Chesapeake.
I've not entirely ignored South America, I had the entire north coast at the time of that post, more since. England was stupid dominant in my game and colonized almost all of South America(Which suits my purposes just fine as I took American culture.) It's 1701(-ish) and there are only 4 CNs controlling all of South America, each of them less than 100% warscore. I'm no huge hurry, but I'll have them taken care of in 4 wars, with a bit of space inbetween to core and convert.
In North America I'm finishing up the heartland. Portugal has California and Alaska, each one war. I've allowed British Louisiana to keep a single province so they can help me finish there. I'm waiting for British Newfoundland to finish up a couple colonies, and that is a <100 WS as well. I'm looking at 10 more wars to totally finish the new world. 8 CNs, Portugal(A couple islands here and there) and England(a single island). When I fight England I'll have a big enough navy to put an 80 stack in Ireland. I think I can take over the area I need for 'For Odin' in the last 100 years without much issue. I took religious and I have missionary strength in my NIs, so I don't think converting will be too big an issue. I'm more worried about spawning a coalition. Worst case scenario I get 'First come, First Serve' this run, and I get For Odin in another run with much better NIs.
I did keep Calvin, but I've disinherited a few heirs throughout the game that were much worse than him. 2 admin is pretty wretched, I probably should have disinherited him. Other than Albert I've had pretty wretched luck with rulers this game <_<