But then you have to care about many different things. You have to cover your front lines, your important industry and infrastructures, etc. And if i recall correctly, if you are a country with high industrial output you have to cover virtually everything which is a pain in the ass.
I think that's very unbalanced for countries that fights against other ones that have a powerful airforce like RAF for Great Britain. They can put all their planes in one strategic region to attack the german reich that has to defend all their country, included probably poland that can be eventually hit by strategic planes.
Not necessary, keep a strong Fighter support on or near the RUHR, and keep smaller fighter/interceptor contingents at - Bremen, Low Countries and Paris (once they fall) and you have pretty much covered everything. If a bomber fleet passes to Berlin, on the way it will be intercepted and fight and lose ORG and material, while returning it will lose some more.
A dozen raids and the entire fleet will have to be rebuilt, far too costly. Thus, until and unless the USA enters the war, Strategic bombing will be minimal.
Obviously, a fighter/interceptor squadron is going to be cheaper and faster built than a Bomber squadron.
Until you get long range support fighters, no Human player will launch futile air raids, against AI it is easier as the AI is predictable.
Also, if by 1943 you have not won Russia, it is game over for Germany, if you have won Russia you can put a thousand fighters all over your territory and then keep a thousand in reserve.