He's talking about the ships going west, across the pacific, those left from Acapulco, in what is now Mexico.what? peru! that incorrect as panama was were all the south american andeas and pacific coeast goods were sent before sending them to spain, why do you think the portobelo fair was the richest of all latin america an targeted so much by pirates!, all the expeditions to peru and argentina departed fom panama too!, even francisco pizarro conqueror of peru was sent first to pacify indians in the middle of panama before going to peru(further more it was in panama that spain learned about the existant of peru and its abundance in gold)( and let me add he had a bigger force for this task than for his expedition to peru and he failed miserably at it by the way) i really hope PI get this right as they always screw panama territory!
Also, relax.
Historically the American gold that went across the pacific arrived first in Manilla and spread across (south-)east Asia from there. But i would hope that the trading patterns would depend on colonisation patterns and not be hardcoded.linking up somewhere in the Far East, perhaps around China, Japan, or the Philippines. That's what the Spanish did during this era